Faculty Details - Dr. B.T. Prabhakar

Dr. B.T. Prabhakar MSc, PhD

Professor

Department - Biotechnology

  • Area Of Specialization:

    Cancer Biology, Immunotherapy

  • Contact:

    Phone: 9632872467
    Email: pbtssc@gmail.com

Projects

Sl No Title Name of Faculty Funding Agency Grants Periods Status
1 Elucidation of molecular mechanism underlying anti-angiogenic pathway by screening of novel bioactive molecules from traditional medicinal plants Prabhakar btDST 23 2012-16 Completed
2 Mechanism based validation of novel bioactive compounds from Helictresisora - Role in anti-angiogenic therapy Prabhakar btUGC-MRP 13.17 2012-16 Completed
3 Mechanism based validation of novel antiangiogenic molecule stargeting hypoxia signaling: A drug development for cancer therapeutics Prabhakar btDBT 25 2015-19 Completed
4 Defining the role of micronutrient Zn + in regulation of NF- Kb signaling mediated inflammatory response: Therapeutic application for Rheumatoid arthritis Prabhakar btVGST 30 2014-22 Completed
5 Unravelling the NEDD9-Vimentin nexus in Head and Neck Squamous Cell Carcinoma interceded cellular invasion and metastasis for cancer therapeutics Prabhakar btSERB 69.96 2019-23 Completed

Publication

Sl No Title Authors Publisher Year
1 Butyrateinduced proapoptotic and antiangiogenic pathways in EAT cells require activation of CAD and downregulation of VEGF Madesh Belakavadi , B.T. Prabhakar , Bharathi P. Salimath Biochemical and Biophysical Research Communications 2005
2 Plant Based Dietary Lectins: Promise for Future Immunotherapeutics Shruthishree D Padiyappa, Hemavathi Avalappa, Siddanakoppalu N Pramod, Bettadatunga T Prabhakar, Zhenxing Li, Yeldur P Venkatesh Taylor & Francis- Food Reviews International 2025
3 Immunomodulatory lectin from Cordia myxa targets PI3K/AKT signalling mediated apoptosis to regress both in-vitro and in-vivo tumour BM Siddesh, BK Kiran, Ankith Sherapura, Riaz Mahmood, N Suchetha Kumari, BT Prabhakar Elsevier- International Journal of Biological Macromolecules 2025
4 Withaferin-A induced vimentin S56 phosphorylation dissociates NEDD9 signaling loop to regress progressive metastatic melanoma into lung adenocarcinoma Ankith Sherapura, BK Kiran, GS Pavan Kumar, BM Siddesh, Prabhu Thirusangu, N Suchetha Kumari, BT Prabhakar Elsevier-Chemico-Biological Interactions 2025
5 Steroidal alkaloid solanidine impedes hypoxia-driven ATM phosphorylation to switch on anti-angiogenesis in lung adenocarcinoma Ankith Sherapura, BM Siddesh, Vikas H Malojirao, Prabhu Thirusangu, BR Vijay Avin, N Suchetha Kumari, YL Ramachandra, BT Prabhakar Elsevier- Phytomedicine 2023
6 Biocompatibility of hydrophilic regenerated Antheraea mylitta silk fibroin Shruti Dixit, Tilak Gasti, Ankith Sherapura, BT Prabhakar, Shyam Kumar Vootla Journal of Applied Biology and Biotechnology 2023
7 Corosolic Acid Inhibits Secretory Phospholipase A2IIa as an Anti-Inflammatory Function and Exhibits Anti-Tumor Activity in Ehrlich Ascites Carcinoma Bearing Mice Sophiya Pundalik, Krishna Ram Hanumappa, Aladahalli S Giresha, Deepadarshan Urs, Sharath Rajashekarappa, Narayanappa Muniyappa, Manjunatha Jamballi G, Devaraju Kuaramkote Shivanna, Rajkumar S Meti, Sathisha Anekere Dasappa Setty, Prabhakar Bettadathunga Thippegowda, Dharmappa Kattepura Krishnappa Taylor & Francis- Journal of Inflammation Research 2022
8 Characterization of antioxidant, anti-cancer, and immunomodulatory functions of partially purified garlic (Allium sativum L.) lectin Shruthishree D Padiyappa, Hemavathi Avalappa, Yeldur P Venkatesh, Nagaraj Parisara, BT Prabhakar, Pramod SN Biomedicine 2022
9 Immunomodulatory and radioprotective property of glucans isolated from Lactobacillus species. Pradeepa, Anushri Umesh, Manasadeepika, Anushree Manjunath, Chithralekha Salian, SM Darshini, BT Prabhakar, Srinivas Mutalik, BK Manjunatha, SM Vidya Bioactive Carbohydrates and Dietary Fibre 2022
10 Immunomodulatory and radioprotective property of glucans isolated from lactobacillus species Anushri Umesh, Anushree Manjunath, Chithralekha Salian, SM Darshini, BT Prabhakar, Srinivas Mutalik, BK Manjunatha, SM Vidya Elsevier-Bioactive Carbohydrates and Dietary Fibre 2022
11 Immunoadjuvant and Humoral Immune Responses of Garlic (Allium sativum L.) Lectins upon Systemic and Mucosal Administration in BALB/c Mice Shruthishree D Padiyappa, Hemavathi Avalappa, Madhusudana Somegowda, Shankarappa Sridhara, Yeldur P Venkatesh, Bettadatunga T Prabhakar, Siddanakoppalu N Pramod, Mona S Almujaydil, Shadi Shokralla, Ashraf MM Abdelbacki, Hosam O Elansary, Ahmed M El-Sabrout, Eman A Mahmoud MDPI- Molecules 2022
12 Anti-neoplastic pharmacophore benzophenone-1 coumarin (BP-1C) targets JAK2 to induce apoptosis in lung cancer Ankith Sherapura, Vikas H Malojirao, Prabhu Thirusangu, BS Sharath, Shivananda Kandagalla, V Vigneshwaran, Jurica Novak, Lakshmi Ranganatha, YL Ramachandra, Shrinath M Baliga, Shaukath Ara Khanum, BT Prabhakar Springer US- Apoptosis 2022
13 Characterization and biochemical activities of novel functional antimicrobial peptide (AMP) from Trichogramma chilonis. Shimoga V Sunil, Hulikal S Santosh Kumar, Siddanakoppalu N Pramod, Betadthunga T Prabhakar, Mahanthesh BN Naika, Thippande G Thippeswamy, Pathappa Niranjana Biomedicine, 2022
14 Antiproliferative pharmacophore azo-hydrazone analogue BT-1F exerts death signalling pathway targeting STAT3 in solid tumour Banumathi, Ankith Sherapura, Vikas H Malojirao, Zabiulla, BS Sharath, Prabhu Thirusangu, Riaz Mahmood, N Suchetha Kumari, Shrinath M Baliga, Shaukath Ara Khanum, BT Prabhakar Springer international-Pharmacological Reports 2022
15 Synthesis, Structure Analysis, DFT Calculations and Energy Frameworks of new Coumarin Appended Oxadiazoles, to Regress Ascites Malignancy by Targeting VEGF Mediated Angiogenesis Mahima Jyoti Banumathi Prabhakar bt Shaukat H Ara Khanum Elsevier- Journal of molecular structure 2021
16 Modulation of DNA damage response by targeting ATM kinase using newly synthesized di-phenoxy acetamide (DPA) analogs to induce anti-neoplasia Shaukath Ara Khanum & B. T. Prabhakar Fares Hezam Al-Ostoot, Ankith Sherapura, Vikas H. Malojirao, Prabhu Thirusangu, Tahani I. Al-Muhimeed Springer international-Pharmacological Reports 2021

Papers

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Conference

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Other Activities

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